Talk to us: +977 1 4102891

Rosutab-5

Dosage Form:- Tablet
Generic Name:- Rosuvastatin 5 mg
Manufactured By:- National Healthcare Pvt. Ltd.

Information

Rosutab-5 is a brand name of Rosuvastatin 5 mg Tablet that belongs to a group of medicines called statins.


Therapeutic Class

HMG-Co.A Reducatse Inihibitor (Lipid Lowering Agent)


Dose and Direction of Use

Rosutab-5 is to be taken orally. Rosuvastatin can be taken with or without food at any time of day.


Mode of Action

Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor for cholesterol. The primary site of action of rosuvastatin is the liver, the target organ for cholesterol lowering.

Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.


Uses

1. Treatment of hypercholesterolemia

2. Prevention of cardiovascular events

 


Contraindications

-Hypersensitivity to Rosuvastatin

- Active liver disease

- Severe renal impairment (Creatinine Clearance <30ml/min)

- Pregnancy and Lactation

 


Precautions and Warning

-Rosuvastatin should be used with caution in patients who consume excessive quantities of alcohol and/have a history of liver disease.

- Should be used in patients with predisposing factors to myopathy.

- The dose should be reduced to 5 mg in patients with moderate renal impairment.

 


Other Medicines with Generic Rosuvastatin 5 mg

This medicine has been viewed 368 times and last modified on 2020-10-06 14:54:26

National Healthcare Pvt. Ltd.


X