Rosutab-5
Tablet
Dose Type
Rosuvastatin 5 mg
Generic Name
National Healthcare Pvt. Ltd.
Manufactured By
Information
Rosutab-5 is a brand name of Rosuvastatin 5 mg Tablet that belongs to a group of medicines called statins. It is used to lower cholesterol and to reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart attack or stroke.
Therapeutic Class
HMG-Co.A Reducatse Inihibitor (Lipid Lowering Agent)
Dose and Direction of Use
Rosutab-5 is to be taken orally. Rosuvastatin can be taken with or without food at any time of day.
Mode of Action
Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor for cholesterol. The primary site of action of rosuvastatin is the liver, the target organ for cholesterol lowering.
Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.
Uses
1. Treatment of hypercholesterolemia
2. Prevention of cardiovascular events
Contraindications
Don't use this medicine if you have:
- Hypersensitivity to Rosuvastatin
- Active liver disease
- Severe renal impairment (Creatinine Clearance <30ml/min)
- Pregnancy and Lactation
Precautions and Warning
- Inform your doctor if you experience fatigue, muscle weakness or muscle pain
- If you are diabetic, monitor your blood sugar level regularly as this tablet may cause an increase in your blood sugar level
- Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.
- It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food
- It should be taken in addition to regular exercise and low-fat diet.
- Don't double the dose for the missed one.
- Complete the prescribed dose and duration of medicine.