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Rosutab-10

Dosage Form:- Tablet
Generic Name:- Rosuvastatin 10 mg
Manufactured By:- National Healthcare Pvt. Ltd.

Information

Rosutab-10 is a brand name of Rosuvastatin 10 mg Tablet that belongs to a group of medicines called statins.


Therapeutic Class

HMG-Co.A Reducatse Inihibitor (Lipid Lowering Agent)


Dose and Direction of Use

Rosutab-10 is to be  taken orally. Rosuvastatin can be taken with or without food at any time of day.


Mode of Action

Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor for cholesterol. The primary site of action of rosuvastatin is the liver, the target organ for cholesterol lowering.

Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles.


Uses

- Treatment of hypercholesterolemia

-  Prevention of cardiovascular events


Contraindications

-Hypersensitivity to Rosuvastatin

- Active liver disease

- Severe renal impairment (Creatinine Clearance <30ml/min)

- Pregnancy and Lactation


Precautions and Warning

- Rosuvastatin should be used with caution in patients who consume excessive quantities of alcohol and/have a history of liver disease.

- Should be used in patients with predisposing factors to myopathy.

- The dose should be reduced to 5 mg in patients with moderate renal impairment.


Other Medicines with Generic Rosuvastatin 10 mg

This medicine has been viewed 384 times and last modified on 2020-10-06 14:53:32

National Healthcare Pvt. Ltd.


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