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Dosage Form:- Cream
Generic Name:- Hydroquinone 2 % w/w + Tretinoin 0.05 % w/w + Fluticasone 0.025% w/w
Manufactured By:- National Healthcare Pvt. Ltd.


Melacort penetrates to deeper layers of the skin which directly helps to fade melasma, freckles, dark spots, and discoloration. The cream is for external use only.

Therapeutic Class

Anti inflammatory + Corticosteroid

Dose and Direction of Use

This combination cream is applied once a day. Apply on a clean face and on the affected areas only and gently massage till it absorbs into the skin. Use it daily at night. Do not use this combination for more dosage often than prescribed by your doctor. Avoid contact with the eyes, eyelids, inside of the nose and mouth, which are easily irritated areas, or other areas where treatment is not intended. Do not apply to severely inflamed skin or to open lesions.


Mode of Action

Hydroquinone: The accumulation of skin pigment called Melanin causes skin darkening. Hydroquinone produces reversible lightening of the skin by interfering with melanin production by the melanocytes. 

 Tretinoin: Although the exact mode of action of tretinoin is unknown, current evidence suggests that topical tretinoin decreases cohesiveness of follicular epithelial cells with decreased microcomedo formation. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells causing extrusion of the comedones.

 Fluticasone Propionate: It is a topical corticosteroid having anti-inflammatory, antipruritic, and vasoconstrictive properties.


Treatment of Melasma


Allergic to fluticasone, hydroquinone, tretinoin or any ingredients in the cream

Pregnant or are breastfeeding, as tretinoin may cause birth defects

Having acute eczema, as tretinoin can cause severe irritation on eczematous skin

Having a skin condition such as rosacea or perioral dermatitis

Having a viral infection of the skin, tuberculosis, acne rosacea (a chronic skin condition), perioral dermatitis (facial rash around the mouth), fungal skin infections and ulcerative conditions


Precautions and Warning

  • Don't get exposed to sunlight for longer time. Use sunscreen or protected clothing over treated areas for protection.
  • Talk to your doctor if you have any medical condition especially skin condition before using this medication.
  • Don't swallow this medication
  • If it gets in your eye or mouth, rinse it well with water.

This medicine has been viewed 506 times and last modified on 2021-02-09 15:20:33

National Healthcare Pvt. Ltd.