Generic Name:- Sitagliptin 100mg
Manufactured By:- National Healthcare Pvt. Ltd.
Glipsi-100 is a brand name of Sitagliptin 100 mg tablet. It belongs to an oral hypoglycemic agent.
Antidiabetics ( DPP-4 enzyme inhibitor)
Dose and Direction of Use
Sitagliptin is for oral administration. It can be taken with or without food.
Mode of Action
Sitagliptin selectively blocks DPP-4 enzyme which is responsible for inactivation of incretins like GLP-1 & GIP.
This results in glucose dependent stimulation of insulin and decrease in glucagon release.
Thus decreases HbA1C, fasting and post prandial glucose level.gliptin selectively blocks DPP-4 enzyme which is responsible for inactivation of incretins like GLP-1 & GIP.
- Type 2 diabetes mellitus
- Diabetic ketoacidosis
Precautions and Warning
- Pregnancy and lactation
- Caution should be used in renal impairment and dose should be adjusted.
- Hypoglycaemia may occur when used in combination with insulin or a sulphonylurea.