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FIXIM CV

Dosage Form:- Tablet
Generic Name:- Cefixime 200mg + Potassium Clavulanate 125mg
Manufactured By:- National Healthcare Pvt. Ltd.

Information

FIXIM CV is the brand name of combination of Cefixime 200 mg + Potassium Clavulanate 125 mg Tablet. It belongs to a class of Cephalosporin + Beta-lactamse inhibitor antibiotics.


Therapeutic Class

Third Generation Cephalosporin + Beta-lactamse inhibitor


Dose and Direction of Use

- To be swallowed whole with water.

- Consume after meal.


Mode of Action

- Cefixime binds with bacterial transpeptidase and inhibits the cross-linking of Peptidoglycan.

- This leads to bacterial cell wall synthesis inhibition however, resistant bacteria can cleave the beta-lactam ring of cefixime and make it ineffective.

- Potassium Clavulanate saves the beta-lactam ring of cefixime by allowing its own ring to be cleaved and prevents drug resistance.

- In this way FIXIM CV leads to cell wall synthesis inhibition of resistant bacterias.


Uses

- Uncomplicated Urinary Tract Infections (e.g. cystitis, cystourethritis, uncomplicated pyelonephritis)

- Upper Respiratory Tract Infections (URTIs) eg: otitis media, pharyngitis, tonsilitis

- Acute Exacerbations of Chronic Bronchitis

- Uncomplicated Gonorrhoea (cervical/urethral)


Contraindications

Hypersensitivity to Cephalosporin and Beta-lactamse inhibitor


Precautions and Warning

- Cefixime as with other broad-spectrum antibiotics should be prescribed with caution in individuals with a history of colitis.

- Increases in prothrombin times may occur and therefore care should be taken in patients receiving anticoagulant therapy.

- No adequate and well-controlled studies in pregnant women have been reported so Cefixime-Clav should therefore not be used in pregnancy or in nursing mothers unless considered essential by the physician.

 


Other Medicines with Generic Cefixime 200mg + Potassium Clavulanate 125mg

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National Healthcare Pvt. Ltd.