Generic Name:- Colecalciferol 400IU
Manufactured By:- National Healthcare Pvt. Ltd.
Colecalciferol, also known as vitamin D3 is a type of vitamin D found in food and used as a dietary supplement. As a supplement it is used to treat and prevent vitamin D deficiency including rickets. It is also used for familial hypophosphatemia, hypoparathyroidism that is causing low blood calcium, and Fanconi syndrome.
Dose and Direction of Use
For Oral administration and preferably with a meal.
Mode of Action
Colecalciferol (Vitamin D3) produces hormone-like actions,it is converted to Calcitriol (an active form of vitamin D3) inside the body which controls phosphorous and calcium metabolism, bone remodelling and neuromuscular function.
- Prophylaxis of rickets and osteomalacia in children and adults.
- Prophylaxis of rickets in preterm newborns.
- Prophylaxis of vitamin D deficiency in children and adults with an identified risk.
- Prophylaxis of vitamin D deficiency in children and adults with malabsorption.
- Treatment of rickets and osteomalacia in children and adults.
- Hypersensitivity to vitamin D
- Hypervitaminosis D
- Diseases or conditions resulting in hypercalcaemia and/or hypercalciuria
- Severe renal impairment
Precautions and Warning
- Vitamin D should be used with caution in patients with impairment of renal function and the effect on calcium and phosphate levels should be monitored.
- The risk of soft tissue calcification should be taken into account.
- In patients with severe renal insufficiency, vitamin D in the form of colecalciferol is not metabolised normally and other forms of vitamin D should be used
- Caution is required in patients receiving treatment for cardiovascular disease.
- It should be prescribed with caution to patients suffering from sarcoidosis because of the risk of increased metabolism of vitamin D to its active form. These patients should be monitored with regard to the calcium content in serum and urine.
- Allowances should be made for vitamin D supplements from other sources.
- The need for additional calcium supplementation should be considered for individual patients.
- Calcium supplements should be given under close medical supervision.
- Medical supervision is required whilst on treatment to prevent hypercalcaemia.