AZITHRO 500
Generic Name:- Azithromycin 500mg
Manufactured By:- National Healthcare Pvt. Ltd.
Information
Azithromycin is an antibiotic drug which is mostly used to treat respiratory tract infections, skin infections and some sexually transmitted diseases.
Therapeutic Class
An Azalide, a subclass of Macrolide Antibiotics.
Dose and Direction of Use
Can be taken with or without food.
Azithro is usually taken once a day.
Try to taking the medicine at the same time each day.
The usual dose is 500mg a day for 3 to 10 days depending on the infection being treated.
For some infections, dose can be given a one-off higher dose of 1g or 2g.
The dose may be lower for children or for patients with liver or kidney problems.
If you forget to take a dose, take it as soon as you remember, unless it's nearly time for your next one. In this case, just leave out the missed dose and take your next dose as normal.
Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.
Mode of Action
Azithromycin binds to the 23S rRNA of the bacterial 50S ribosomal subunit. It blocks protein synthesis by inhibiting the transpeptidation/translocation step of protein synthesis and by inhibiting the assembly of the 50S ribosomal subunit.
Uses
- Acute bacterial exacerbations of chronic obstructive pulmonary disease
- Acute bacterial sinusitis
- Community-acquired pneumonia
- Pharyngitis/tonsillitis
- Uncomplicated skin and skin structure infections
- Urethritis and cervicitis
- Genital ulcer disease
Contraindications
- Azithro is contraindicated in patients having hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic.
- Azithro is also contraindicated in patients with a history of cholestatic jaundice/hepatic dysfunction associated with prior use of azithromycin.
Precautions and Warning
As azithromycin is principally eliminated via the liver, caution should be exercised when azithromycin is administered to patients with impaired hepatic function.
